Growth Factors
Tesamorelin
GHRH analog
Tesamorelin (trans-3-hexenoyl-GHRH(1-44))
Research context
Tesamorelin is a full-length GHRH(1-44) analogue with a trans-3-hexenoyl group at the N-terminus, which published characterisation associates with resistance to DPP-4 degradation. Research examines GHRH receptor binding and pituitary secretion endpoints.
Common assays: GHRH receptor binding · Pituitary GH secretion · Enzymatic stability
Specification
| Designation | GHRH analog |
|---|---|
| Full name | Tesamorelin (trans-3-hexenoyl-GHRH(1-44)) |
| Sequence | trans-3-hexenoyl-GHRH(1-44) — 44-residue analogue with N-terminal acyl modification |
| CAS number | 218949-48-5 |
| Molecular formula | C221H366N72O67S |
| Molecular weight | 5135.86 g/mol |
| Formats | 10 mL Vial · 15 mL Advanced Liquid Peptide Spray |
| Solubility | Bacteriostatic water, sterile water |
| Storage | Lyophilised: 2–8 °C, protected from light. Reconstituted: 2–8 °C. |
| Current lot | TES10VCS0126 → |
Tesamorelin COA: certificates of analysis by lot
3 lots of Tesamorelin have a published certificate of analysis from AxisPharm, LLC, an independent laboratory. Each certificate reports the laboratory's results for that lot.
| Lot | Format | Purity (HPLC-UV) | Reported |
|---|---|---|---|
| TES10VCS0126 | 10 mg Vial | >99.3% | 2026-02-20 |
| TES10VAS0126 | 10 mg Vial | >99.3% | 2026-02-20 |
| TES10N1125 | 10 mg Spray | >99.0% | 2025-11-13 |
Published literature
Selected peer-reviewed references describing research involving this compound. Listed for reference only; inclusion is not a claim about any outcome.
- Falutz J, Allas S, Blot K, et al.Metabolic effects of a growth hormone-releasing factor in patients with HIVNew England Journal of Medicine · 2007 Find on PubMed ↗
Common questions
How does tesamorelin differ from CJC-1295?
Tesamorelin is the full 44-residue GHRH sequence with an N-terminal acyl modification; CJC-1295 is the shorter 29-residue fragment with four internal substitutions. Both target the same receptor by different stabilisation strategies.
Where can I see the Tesamorelin certificate of analysis?
Every published Tesamorelin lot has its own certificate page on this site, listed under "Tesamorelin COA" above. There are 3 published lots; the most recent, lot TES10VCS0126, was reported on 2026-02-20 at >99.3% purity by HPLC-UV. The certificates are issued by AxisPharm, LLC, an independent laboratory.
Components, blends and pathway
Related compounds
Tesamorelin / Ipamorelin
GH Blend
A prepared blend pairing a full-length GHRH analogue with a selective ghrelin receptor secretagogue.
PT-141 / Oxytocin / Tesamorelin
Peptide blend
A prepared three-component blend spanning melanocortin, oxytocin, and GHRH receptor ligands.
CJC-1295
GHRH analog
A tetrasubstituted analogue of growth hormone-releasing hormone (1-29), studied in pituitary secretion research.
CJC-1295 / Ipamorelin
GH Blend
A prepared blend pairing a GHRH analogue with a selective ghrelin receptor secretagogue.