9 compounds
Longevity & Cellular Renewal
Compounds examined in relation to nicotinamide adenine dinucleotide biosynthesis, sirtuin cofactor availability, mitochondrial function, and replicative senescence markers. Common endpoints include intracellular NAD⁺ quantification, respirometry, telomerase expression, and β-galactosidase staining.
NAD+
Nicotinamide adenine dinucleotide
The central redox cofactor of cellular metabolism and substrate for sirtuins, PARPs, and CD38.
MOTS-C
Mitochondrial-derived peptide
A 16-residue peptide encoded in the mitochondrial genome, studied in AMPK signalling.
SS-31
Elamipretide
A cell-permeable tetrapeptide with affinity for cardiolipin, studied in mitochondrial membrane research.
Humanin
Mitochondrial-derived peptide
A 24-residue mitochondrially encoded peptide studied in cytoprotection and apoptosis research.
Epitalon
Ala-Glu-Asp-Gly tetrapeptide
A synthetic tetrapeptide studied in telomerase expression and pineal signalling research.
GHK-Cu
Copper tripeptide-1
A naturally occurring copper-binding tripeptide studied in extracellular matrix and gene expression research.
Glutathione
Reduced L-glutathione
The principal intracellular thiol antioxidant and substrate for glutathione peroxidase and S-transferases.
Glutathione / Magnesium
Reduced glutathione + magnesium
A prepared blend of reduced glutathione with magnesium.
Methyl B12
Methylcobalamin
The methylated cobalamin cofactor for methionine synthase, studied in one-carbon metabolism.