Longevity & Cellular Renewal
Epitalon
Ala-Glu-Asp-Gly tetrapeptide
Epitalon (Ala-Glu-Asp-Gly tetrapeptide)
Research context
Epitalon is a synthetic tetrapeptide derived from work on pineal peptide preparations. The published literature examines telomerase reverse transcriptase expression and telomere length measurement in cultured human fibroblast models, alongside investigation of melatonin-related signalling.
Common assays: TERT expression (qPCR) · Telomere length (TRF/qPCR) · Melatonin quantification
Specification
| Designation | Ala-Glu-Asp-Gly tetrapeptide |
|---|---|
| Full name | Epitalon (Ala-Glu-Asp-Gly tetrapeptide) |
| Sequence | Ala-Glu-Asp-Gly |
| CAS number | 307297-39-8 |
| Molecular formula | C14H22N4O9 |
| Molecular weight | 390.35 g/mol |
| Formats | 10 mL Vial · 15 mL Advanced Liquid Peptide Spray |
| Solubility | Sterile water, bacteriostatic water |
| Storage | Lyophilised: −20 °C, desiccated. Reconstituted: 2–8 °C. |
| Current lot | EPI100V1125 → |
Published literature
Selected peer-reviewed references describing research involving this compound. Listed for reference only; inclusion is not a claim about any outcome.
- Khavinson VK, Bondarev IE, Butyugov AA.Epithalon peptide induces telomerase activity and telomere elongation in human somatic cellsBulletin of Experimental Biology and Medicine · 2003 Find on PubMed ↗
- Khavinson VK, Popovich IG.Short peptides regulate gene expressionBulletin of Experimental Biology and Medicine · 2020 Find on PubMed ↗
Common questions
What is the difference between Epitalon and Epithalamin?
Epithalamin refers to a peptide preparation extracted from pineal tissue; Epitalon is a defined synthetic tetrapeptide developed from that work. Only the synthetic form has a single defined sequence.
What endpoints appear in the Epitalon literature?
Telomerase reverse transcriptase expression and telomere length measurement, most commonly in cultured human fibroblasts.
Components, blends and pathway
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