Vitality
Oxytocin
Oxytocin
Oxytocin (cyclic nonapeptide)
Research context
Oxytocin is a nonapeptide with an intramolecular disulfide bridge between cysteine residues 1 and 6. Research examines oxytocin receptor binding, cross-reactivity with vasopressin receptors, and downstream signalling in receptor-expressing cell lines.
Common assays: OXTR binding · V1a cross-reactivity · Calcium mobilisation · Receptor internalisation
Specification
| Designation | Oxytocin |
|---|---|
| Full name | Oxytocin (cyclic nonapeptide) |
| Sequence | Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH₂ (disulfide bridged 1–6) |
| CAS number | 50-56-6 |
| Molecular formula | C43H66N12O12S2 |
| Molecular weight | 1007.19 g/mol |
| Formats | 15 mL Advanced Liquid Peptide Spray |
| Solubility | Sterile water, bacteriostatic water |
| Storage | Lyophilised: −20 °C. Reconstituted: 2–8 °C. |
| Current lot | OXY10N1125 → |
Oxytocin COA: certificates of analysis by lot
One lot of Oxytocin has a published certificate of analysis from AxisPharm, LLC, an independent laboratory. Each certificate reports the laboratory's results for that lot.
| Lot | Format | Purity (HPLC-UV) | Reported |
|---|---|---|---|
| OXY10N1125 | 10 mg Spray | >99.0% | 2025-11-20 |
Published literature
Selected peer-reviewed references describing research involving this compound. Listed for reference only; inclusion is not a claim about any outcome.
- Gimpl G, Fahrenholz F.The oxytocin receptor system: structure, function, and regulationPhysiological Reviews · 2001 Find on PubMed ↗
Common questions
Why does oxytocin cross-react with vasopressin receptors?
Oxytocin and vasopressin differ by only two residues, so binding assays routinely include vasopressin receptor subtypes to characterise selectivity.
What is the role of the disulfide bridge?
It forms the six-residue ring defining the peptide conformation. Reduction of the bridge abolishes activity, which is why storage conditions limiting reduction matter.
Where can I see the Oxytocin certificate of analysis?
Every published Oxytocin lot has its own certificate page on this site, listed under "Oxytocin COA" above. There is one published lot; the most recent, lot OXY10N1125, was reported on 2025-11-20 at >99.0% purity by HPLC-UV. The certificates are issued by AxisPharm, LLC, an independent laboratory.
Components, blends and pathway
Related compounds
PT-141 / Oxytocin
Peptide blend
A prepared blend combining a melanocortin receptor agonist with oxytocin.
PT-141 / Oxytocin / Tesamorelin
Peptide blend
A prepared three-component blend spanning melanocortin, oxytocin, and GHRH receptor ligands.
PT-141
Bremelanotide
A cyclic heptapeptide melanocortin receptor agonist studied in MC3R and MC4R signalling.
Melanotan II
Melanotan-II
A cyclic α-MSH analogue studied as a non-selective melanocortin receptor agonist.