Vitality
Melanotan II
Melanotan-II
Melanotan-II (MT-II)
Research context
Melanotan II is a cyclic lactam analogue of α-melanocyte-stimulating hormone characterised as a non-selective agonist across melanocortin receptor subtypes. Research examines melanogenesis in melanocyte culture and receptor binding across the MC1R–MC5R family.
Common assays: Melanogenesis quantification · MC receptor panel binding · Tyrosinase activity
Specification
| Designation | Melanotan-II |
|---|---|
| Full name | Melanotan-II (MT-II) |
| Sequence | Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂ |
| CAS number | 121062-08-6 |
| Molecular formula | C50H69N15O9 |
| Molecular weight | 1024.18 g/mol |
| Formats | 10 mL Vial · 15 mL Nasal Spray · 15 mL Oral Spray |
| Solubility | Sterile water, bacteriostatic water |
| Storage | Lyophilised: −20 °C, protected from light. Reconstituted: 2–8 °C. |
| Current lot | MEL215N0126 → |
Published literature
Selected peer-reviewed references describing research involving this compound. Listed for reference only; inclusion is not a claim about any outcome.
- Hadley ME, Dorr RT.Melanocortin peptide therapeutics: historical milestones, clinical studies and commercializationPeptides · 2006 Find on PubMed ↗
Common questions
What distinguishes Melanotan II from PT-141 structurally?
Melanotan II carries a C-terminal amide; PT-141 has a free carboxyl at that position. The difference is associated with the distinct receptor selectivity profiles reported for each.
Same pathway
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