Neurotropic & Cognitive
DSIP
Delta sleep-inducing peptide
Delta Sleep-Inducing Peptide
Research context
DSIP is a nonapeptide originally isolated during work on sleep-related humoral factors. Research examines electroencephalographic delta activity in animal models, alongside receptor binding and stability characterisation. The literature is comparatively small and the receptor remains incompletely characterised.
Common assays: EEG delta power quantification · Peptide stability · Receptor binding characterisation
Specification
| Designation | Delta sleep-inducing peptide |
|---|---|
| Full name | Delta Sleep-Inducing Peptide |
| Sequence | Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu |
| CAS number | 62568-57-4 |
| Molecular formula | C35H48N10O15 |
| Molecular weight | 848.81 g/mol |
| Formats | 15 mL Advanced Liquid Peptide Spray |
| Solubility | Sterile water, bacteriostatic water |
| Storage | Lyophilised: −20 °C, desiccated. Reconstituted: 2–8 °C. |
| Regulatory status | Not an approved drug. Removed from FDA 503A Category 2 in April 2026; the advisory committee voted against adding it to the 503A bulks list in July 2026. 2026 status by compound → |
| Current lot | DSIP8N0526 → |
DSIP COA: certificates of analysis by lot
One lot of DSIP has a published certificate of analysis from AxisPharm, LLC, an independent laboratory. Each certificate reports the laboratory's results for that lot.
| Lot | Format | Purity (HPLC-UV) | Reported |
|---|---|---|---|
| DSIP8N0526 | 8 mg Spray | 99.2% | 2026-05-27 |
Published literature
Selected peer-reviewed references describing research involving this compound. Listed for reference only; inclusion is not a claim about any outcome.
- Schoenenberger GA, Monnier M.Characterization of a delta-electroencephalogram (-sleep)-inducing peptideProceedings of the National Academy of Sciences · 1977 Find on PubMed ↗
Common questions
Is the DSIP receptor identified?
Not definitively. Despite the peptide being isolated decades ago, a specific receptor has not been conclusively characterised in the published literature — which is itself an active question in the field.
Where can I see the DSIP certificate of analysis?
Every published DSIP lot has its own certificate page on this site, listed under "DSIP COA" above. There is one published lot; the most recent, lot DSIP8N0526, was reported on 2026-05-27 at 99.2% purity by HPLC-UV. The certificates are issued by AxisPharm, LLC, an independent laboratory.
Components, blends and pathway
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