Neurotropic & Cognitive
DSIP
Delta sleep-inducing peptide
Delta Sleep-Inducing Peptide
Research context
DSIP is a nonapeptide originally isolated during work on sleep-related humoral factors. Research examines electroencephalographic delta activity in animal models, alongside receptor binding and stability characterisation. The literature is comparatively small and the receptor remains incompletely characterised.
Common assays: EEG delta power quantification · Peptide stability · Receptor binding characterisation
Specification
| Designation | Delta sleep-inducing peptide |
|---|---|
| Full name | Delta Sleep-Inducing Peptide |
| Sequence | Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu |
| CAS number | 62568-57-4 |
| Molecular formula | C35H48N10O15 |
| Molecular weight | 848.81 g/mol |
| Formats | 15 mL Nasal Spray · 15 mL Oral Spray |
| Solubility | Sterile water, bacteriostatic water |
| Storage | Lyophilised: −20 °C, desiccated. Reconstituted: 2–8 °C. |
Published literature
Selected peer-reviewed references describing research involving this compound. Listed for reference only; inclusion is not a claim about any outcome.
- Schoenenberger GA, Monnier M.Characterization of a delta-electroencephalogram (-sleep)-inducing peptideProceedings of the National Academy of Sciences · 1977 Find on PubMed ↗
Common questions
Is the DSIP receptor identified?
Not definitively. Despite the peptide being isolated decades ago, a specific receptor has not been conclusively characterised in the published literature — which is itself an active question in the field.
Same pathway
Related compounds
Semax
ACTH(4-10) analog
A synthetic ACTH(4-10) analogue extended with Pro-Gly-Pro, studied in neurotrophic factor expression.
Selank
Tuftsin analog heptapeptide
A synthetic tuftsin analogue with a stabilising Pro-Gly-Pro extension, studied in GABAergic signalling.
Semax / Selank
Peptide blend
A prepared blend of two Pro-Gly-Pro stabilised heptapeptides.
